Awarded Students
Natural Compounds Chemistry – Synthesis
- Adam Beniš (M2): Synthesis of Methoxphenidine Analogues
- Viktorja Brhlová (M2): Thiol–Ene Strategy for the Synthesis of Glycomimetics for Galectin Inhibition
- Kateřina Žďárková (M2): Preparation and Characterization of BODIPY-Labelled Colchicines and Their Biological Evaluation
Natural Compounds Chemistry – Analytical Chemistry
- Evelína Čížková (M2): Determination of Biologically Active Compounds in Centella asiatica (Centella asiatica(L.) Urb.)
- Ondřej Šlachta (M2): Isolation of Selected Secondary Metabolites from Mesembryanthemum tortuosum
- Maria Kučerková (M2): Study of the Pharmacokinetics of Cycloastragenol in Brain Tissue
Natural Compounds Chemistry – Synthesis
- Ondřej Bilák (M2): Synthesis and Characterization of Artemisinin Derivatives with a 3,5-Difluorophenyl Group
- Lenka Bendová (M2): Stereoselective Synthesis of Isotopically Labelled 15N-Aminosugars
- Kateřina Žďárková (M1): Preparation and Characterization of BODIPY-Labelled Colchicine Derivatives and Their Biological Evaluation
- Viktor Káčerik (M2): Preparation of New γ-Tubulin Inhibitors
Natural Compounds Chemistry – Analytical Chemistry
- Aneta Pintová (M2): Optimization of Conditions for the Photocatalytic Degradation of Methamphetamine in Water and Analysis of the Resulting Intermediates
- Evelína Čížková (M1): Comparison of Adaptogenic Plants: Spectrophotometric Determination of Saponin Content and Antioxidant Activity
- David Šmidlík (M2): Development of a Multiplex LFIA Method for the Analysis of Anabolic Androgenic Steroids (AAS)
- Maria Kučerková (M1): Study of the Pharmacokinetics of Cycloastragenol Administered in a Liposomal Formulation
Natural Compounds Chemistry I
(two second prizes)
- Marek Vurm (M2): Determination of Tryptamine Alkaloids and Their Metabolites in the Urine of Patients Suffering from Postoperative Delirium after Cardiac Surgery
- Dominik Lovás (M2): Secondary Metabolites of the Genus Exobasidium (Fungi: Basidiomycota) and Their Biotechnological Significance
- Adéla Bohatá (M2): Determination of Selected Secondary Metabolites in Representatives of the Genus Amanita by HPLC-MS
- Michaela Maříková (M2): Development and Validation of an LC-MS Method for the Determination of Ketamine, Norketamine, and Midazolam in Human Serum in a Clinical Evaluation of Depression Treatment
Natural Compounds Chemistry II
(two third prizes)
- Hana Fuxová (M2): Modelling Study of Interactions of 3-Sulfopropionic Acid and Its Analogues and Precursors with Aβ Peptides
- Michal Fischer (M2): Synthesis of Mannose-6-Phosphate Analogues
- Adam Rybka (M2): Synthesis of Isotopically Labelled 15N-Aminosugars for NMR Structural Analysis
- Klára Mansfeldová (B3): An Innovative Approach to α-Aryl-S-Glycosides
Natural Compounds Chemistry I
- Karel Tůma (M2): Stereoselective Synthesis of β-C-Mannopyranosides
- Rostislav Kleveta (M2): Synthesis and Immobilization of Fluorinated Hexosamines on Multivalent Carriers
- Věra Šmelíková (M2): Stereoselective Synthesis of Diglycosylazoles and Their Applications
Natural Compounds Chemistry II
- Dominika Mrázková (M1): Modelling of Binding Affinities of Fentanyl Derivatives to the Mu-opioid receptor
- Julie Jindrová (M2): Determination of Ketamine in a Clinical Evaluation of Treatment of Pharmacoresistant Depression
- Petra Hlavatá (M2): Preparative Chiral Separation of Synthetic Cathinones for the Study of Their Bioactivity
Natural Compounds Chemistry I
- Dana Králová (M2): Stereo- and Regioselectivity of Photochemical Radical Addition in the Synthesis of S-Glycosides
- Karel Tůma (M1): Stereoselective Synthesis of C-Glycosides from 2,3:4,6-di-O-isopropylidene-D-glucal
- Natálie Šiplerová (M2): Pyrazine Motif in the Derivatization of Selected Triterpenoids, Their Self-Assembly, and Biological Activity
Natural Compounds Chemistry II
- Kateřina Knížková (M2): Determination of Bioactive Compounds of Rhaponticum carthamoides
- Kateřina Obytová (M2): Determination of Cannabidiol and Its Metabolites in Rat Serum by HPLC-MS
- Lukáš Mazur (M2): Effect of Epigenetic Changes on Selected Phytohormones and Transcripts Involved in Plant Immune Response
Natural Compounds Chemistry I
- Kateřina Novotná (M2): Synthesis of S-Oligosaccharides for Inhibition of HIV Infectivity
- Pavel Trousil (M2): Synthesis and Study of Mitotic Inhibitors Derived from Estradiol
- Hedvika Češková (M1): Synthesis of Selected Metabolites of the New Psychoactive Substance 2CB-Fly-NBOMe
Natural Compounds Chemistry II
- Terézia Hladká (M1): Structural Analogues of the PF74-Type HIV-1 Inhibitor and Preparation of a New HIV System
- Lea Bartoňová (M1): Modelling of Interactions of New Synthetic Drugs with Receptors
- Dana Králová (M1): Preparation of S-Oligosaccharides and Glycosides Using a Photochemical Radical Reaction
Natural Compounds Chemistry II – Analytical Chemistry
- Anna Marešová (M2): TZ6019 Isomer Labelled with I-123 and I-125 for Imaging of the P2X7 receptor
- Petr Lexa (M1): Cunninghamella elegans as an in vivo Model of Deschloroketamine Metabolism
- Denisa Adamcová (M2): Development of an in vitro Method for Transcorneal Transport of Cannabinoids
Natural Compounds Chemistry I
- Daniel Heblík (M2): Identification of Metabolites of 5-MeO-DMT in Volunteers’ Urine by LC-HRMS
- Leona Palbuchtová (M1): Analysis of Selected Endogenous Steroids in Biological Matrices by HPLC-MS
- Angelika Beata Pelc (M1): Identification of Synthetic Cannabinoids by Raman and Infrared Spectroscopy
Natural Compounds Chemistry II
- Václava Susan Holinková (M2): Development of an Immunoanalytical Method for the Determination of 21-Deoxycortisol
- Dana Králová (B3): Stereoselective Preparation of S-Oligosaccharides
- Michaela Křivská (M2): Modification of Insulin to Influence the Selectivity of Interactions with Isoforms of the Insulin Receptor
- Kryštof Škach (M2): Design, Synthesis, and Study of HIV-1 Inhibitors
- Tomáš Otava (M2): New Antiviral Derivatives Based on Nucleosides and Nucleotides
- Natálie Kolderová (M2): Chiral Separation of Deschloroketamine and Its Metabolites by Supercritical Fluid Chromatography
- Karolína Vaňková (M1): Synthesis of New (1→1)-C-Disaccharides
Natural Compounds Chemistry I
- Michal Rahm (M1): Synthesis of Glycomimetics Using the Hiyama Reaction
- Jakub Zýka (M2): Preparation of Isosteric Nucleoside Phosphonates and Derived Monomers
- Vít Prouza (M2): Synthesis of Aryl C-Glycosides and Their Use in Cellular Recognition
Natural Compounds Chemistry II
- Jaroslava Šmolíková (M1): Structured Peptides as Enzyme Inhibitors
- Martina Mejzrová (M2): Peptides with HIV-1 Inhibitory Properties
- Markéta Šišáková (M2): Polyvalent Fucosylcalixarenes as Ligands of Lectins from Pathogenic Bacteria
Natural Compounds Chemistry – Analytical Chemistry
- Lucie Svobodová (B3): Identification of New Psychoactive Substances by Raman and Infrared Spectroscopy
- Barbora Mužiková (B3): Identification of New Psychoactive Substances by NMR
- Tereza Maříková (B3): Development of a Method for Preparative Enantioseparation of Synthetic Cathinones
Section I
- Vít Prouza (M1): Stereoselective Preparation of Sugar Ligands for Recognition at the Cellular Level
- Michal Rahm (B3): Synthesis of New Glycomimetics Using the Hiyama Reaction
- Jakub Zýka (M1): Preparation of Nucleotide 3′-Phosphonates for Solid-Phase Synthesis
- Dorota Konvalinková (M2): Preparation of Water-Soluble Glycomimetics
Section II
- Kryštof Škach (M1): Synthesis and Study of a Bombesin Analogue with Photosensitizers
- David Kodr (M1): Synthesis of Conjugates of Cyproterone with Photosensitizers
- Alice Kovářová (B3): Analysis of Phytocannabinoids in Cosmetic and Medicinal Products by GC-MS and LC-MS
- Radka Kucherková (M1): Synthesis of Methoxy Derivatives of BODIPY Dyes
Section I
- Andrea Vlachová (M2): Immunochemical Detection of Orally Active Anabolics
- David Kodr (B3): Synthesis of Conjugates of Cyproterone and Purpurin 18
- Angelina Anufrieva (M1): Use of Fatty Acid Derivatives for the Preparation of Ceramides
- Karla Nováková (M2): A New Synthetic Approach to the Synthesis of C-Glycosides and C-Disaccharides
Section II
- Jaroslava Šmolíková (B3): Argireline Analogues Modified with Triterpenes
- Vít Prouza (B3): Preparation of Multifunctional Sugar Ligands for Recognition at the Cellular Level
- Alice Kovářová (B2): Analysis of Phytocannabinoids in Cosmetic and Medicinal Products by GC-MS
- Pavla Průchová (B3): Analysis of Commercial Products Containing Tribulus terrestris by HPLC-MS
Section I
- Tomáš Jandušík (M2): Modified Oligoadenylates as Potential Effectors of Ribonuclease
- Dominika Jírová (M2): Development of an Immunochemical Test for the Determination of Stanozolol
- Šárka Bicanová (B3): Components of Immunochemical Kits for the Detection of Synthetic Cannabinoids
- Tomáš Zimmermann (M2): Modification of the Pharmacophores of Trilobolide
Section II
- Jan Choutka (M2): Preparation of (1→2)-C-Disaccharides Using the Suzuki–Miyaura Reaction
- Lucie Čechová (M2): Separation and Characterization of Rotamers of 5-Nitrosopyrimidines Stabilized by Intramolecular Hydrogen Bonds
- Lenka Erhartová (M2): Preparation of New Glycoclusters Using a Pd-Catalysed Reaction
- Lucie Čechová (M1): Synthesis of Polysubstituted 5-Nitrosopyrimidines and Their Physicochemical Properties
- Ondřej Longin (M2): Synthesis of Haptens Derived from Sex Hormones
- Lenka Erhartová (M1): Preparation of New Glycoclusters Using a Pd-Catalysed Reaction
- Kristýna Řepková (M1): Pd-Catalysed Synthesis of a C-Analogue of the Tn Antigen
- Šárka Salajková (M2): Effect of Brassinosteroids on the Content of Ecdysteroids in Plants
- Tomáš Zimmermann (B3): Modification of the Pharmacophore of Trilobolide
- Michal Jurášek (M2): Steroids for Supramolecular Chemistry
- Michaela Novotná (M2): Isomerization of Silybins
- Ladislav Trnka (M2): Hybrid QM/QM ONIOM Method for Accurate Calculations of Large Molecules: Calculation of NMR Spectra of Phenanthroline Cholaneamide
- Radka Břízová (M2): Volatile Compounds Produced by Anastrepha fraterculus
- Vít Novák (M2): Prediction of Spectral Properties of Carbohydrates Using Hybrid QM/MM Calculations
- Michal Jurášek (M1): Steroid “Click Tripods”: Synthesis and Properties
- Michaela Boulová (M2): Preparation of Steroid Oligopyrrolic Macrocycles and Their Applications
- Tereza Přichystalová (M2): Synthesis of Steroid Derivatives of Spermine
- Markéta Řehová (M2): Design of the Synthesis of 3-Deoxy-3-(α-D-glucopyranosylmethyl)-D-1-deoxynojirimycin
- Eva Kubíčková (B3): New Dithioacetal of 2-Deoxy-2-thio-D-talose
- Pavla Balátová (M2): Polyphenols of Humulus lupulus
- Beata Jonsztová (M2): Reduction of Amide Conjugates
- Zuzana Lövyová (5th year): Synthesis of a Precursor of β-C-(1→3)-Disaccharide
- Hana Svobodová (5th year): Steroid Derivatives of Biologically Active Alcohols
- Lukáš Novotný (5th year): Ab initio and DFT Calculations of NMR Spectra of Bicyclic Methylerythrofuranosides with a Three-Membered Heterocyclic Ring
- Zdeňka Černovská (5th year): Methods for Testing the Activity of Galactosyltransferase Inhibitors
- Elena Prokudina (5th year): Immunoaffinity Sorbents for Isoflavonoids
- Jana Tomanová (5th year): Conjugates of D-Glucosamine with Steroid and Bile Acids Linked by an Amide Bond
- Jan Horníček (5th year): Parameterization of the MM3 Force Field
- Zdeňka Černovská (4th year): Staudinger–Aza-Wittig Reaction of 3-O-Acetylated Derivatives of Methyl-2-azido-2-deoxy-α-D-mannopyranoside
- Lenka Šimková (5th year): Preparation of a New Type of Cyclic Phosphoric Acid Esters
- Jarmila Juklová (5th year): Intramolecular Aza-Wittig Reaction in the Reduction of Azidodeoxymannosides
- Jan Horníček (4th year): Solvent Simulation for the Conformational Analysis of Carbohydrates
- Lenka Šimková (4th year): Stability of the Acetal Group under Arbuzov–Michaelis Reaction Conditions
- Kamil Parkan (5th year): Use of a Chiral Imine for the Selective Control of the Aza-Diels–Alder Reaction