doc. Ing. Dominik Rejman, CSc.

Education and Experience

From 2026              Head of the Laboratory of Antimicrobial Agents: joint laboratory of UCT Prague and IOCB

2022                      Habilitation at the Faculty of Medicine, Palacký University Olomouc (Associate Professor)

From 2005              Institute of Organic Chemistry and Biochemistry (IOCB)

2004                      Center for Drug Design, University of Minnesota, USA

2002 – 2004           Institute of Organic Chemistry and Biochemistry (IOCB)

2002 – 2004           Department of Chemistry, University of Sheffield

1996 – 2001           Doctoral studies (Supervisor: Ing. Ivan Resenberg, CSc.)

1992 – 1996           Master's studies at the Department of Organic Chemistry, UCT Prague (Ing.)

Teaching

Since 2016          Lectures and microbiology course, Faculty of Medicine, Palacký University Olomouc

Research Interests

Organic chemistry; chemistry and biology of antimicrobial compounds; chemistry and biological properties of modified nucleic acids.

A key aspect of my research is the development of molecular tools that assist microbiologists, biologists, and biochemists in studying resistance mechanisms and bacterial regulatory processes. Additionally, I work on developing inhibitors of nucleotide biosynthesis as potential antimicrobial agents. My primary research focuses on lipophosphonoxins—membrane-targeting compounds with potent antibacterial properties. We have successfully tested these compounds in nanofiber wound dressings for treating *Staphylococcus aureus* wound infections in a mouse model.

Awards

2007                 Alfred Bader Award