Ing. Ondřej Kostov, Ph.D.

Education

University of Chemistry and Technology, Prague, Faculty of Food and Biochemical Technology, Department of Chemistry of Natural Compounds (UCHPL)
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

2011 – 2018         Doctoral Studies: Synthesis of Biologically Significant Oligonucleotides Modified at the Internucleotide Linkage (Ph.D.)
Supervisor: Ing. Ivan Rosenberg, CSc.

University of Chemistry and Technology, Prague, Faculty of Food and Biochemical Technology, Department of Chemistry of Natural Compounds

2009 – 2011         Master's Study: Stereoselective Synthesis of 3-C-[(β-D-Glucopyranosyl)methyl]-D-glucose (Ing.)
Supervisor: doc. Ing. Ladislav Kniežo, CSc.

2005 – 2009         Bachelor's Study: Synthesis of tetra-O-acetyl-α-glucopyranosylpropene (bc.)
Supervisor: doc. Ing. Ladislav Kniežo, CSc.

Experience

2018 – 2026         Postdoc at University of Colorado Boulder (USA) prof. Marvina H. Caruthers group

Research Interest

Nucleic acid chemistry

Design and synthesis of oligonucleotides

Gene regulation and biological interactions

Chemistry of selective cell targeting

Awards

Ondřej Kostov, Ph.D.; Jay R. Hesselberth, Ph.D.; University of Colorado, Fall 2022 AB Nexus Grant Awards; New Collaborations ($50,000); Gene-specific antisense oligonucleotide therapies for diseases of haploinsufficiency