Doctoral studies
Ing. Anna Marešová
Masters's degree
bc. Lukáš Mazur
bc. František Fiala
bc. Jan Mazel
Bachelor's degree
Gabriela Merhoutová
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Technická 5
166 28 Prague 6 – Dejvice
IČO: 60461337
VAT: CZ60461373
Data mail: sp4j9ch
Copyright: UCT Prague 2015
Information provided by the Department of International Relations and the Department of R&D. Technical support by the Computing Centre. [paticka_odkaz_mail] => mailto:Ondrej.Simak@vscht.cz [social_fb_title] => [social_tw_title] => [social_yt_title] => [google_search] => 001523547858480163194:u-cbn29rzve [drobecky] => You are here: UCT Prague - FFBT - UCHPL [aktualizovano] => Updated [autor] => Author [paticka_mapa_alt] => [stahnout] => Download [intranet_odkaz] => http://intranet.vscht.cz/ [intranet_text] => Intranet [logo_mobile_href] => / [logo_mobile] => [mobile_over_nadpis_menu] => Menu [mobile_over_nadpis_search] => Search [mobile_over_nadpis_jazyky] => Languages [mobile_over_nadpis_login] => Login [menu_home] => Homepage [zobraz_desktop_verzi] => switch to desktop version [zobraz_mobilni_verzi] => switch to mobile version [paticka_mapa_odkaz] => [nepodporovany_prohlizec] => For full access, please use different browser. [preloader] => Wait a second... [social_in_odkaz] => [social_li_odkaz] => [more_info] => ) [poduzel] => stdClass Object ( [6151] => stdClass Object ( [obsah] => [poduzel] => stdClass Object ( [6154] => stdClass Object ( [obsah] => [iduzel] => 6154 [canonical_url] => //uchpl.vscht.cz [skupina_www] => Array ( ) [url] => [sablona] => stdClass Object ( [class] => [html] => [css] => [js] => [autonomni] => ) ) [6152] => stdClass Object ( [obsah] => [iduzel] => 6152 [canonical_url] => //uchpl.vscht.cz [skupina_www] => Array ( ) [url] => [sablona] => stdClass Object ( [class] => [html] => [css] => [js] => [autonomni] => ) ) [6153] => stdClass Object ( [obsah] => [iduzel] => 6153 [canonical_url] => //uchpl.vscht.cz [skupina_www] => Array ( ) [url] => [sablona] => stdClass Object ( [class] => [html] => [css] => [js] => [autonomni] => ) ) ) [iduzel] => 6151 [canonical_url] => [skupina_www] => Array ( ) [url] => [sablona] => stdClass Object ( [class] => [html] => [css] => [js] => [autonomni] => ) ) [6180] => stdClass Object ( [obsah] => [poduzel] => stdClass Object ( [12485] => stdClass Object ( [nazev] => Studies [seo_title] => Studies [seo_desc] => Studies Department of Chemistry of Natural Compounds at the Faculty of Food and Biochemical Technology UCT Prague University of Chemistry and Technology Prague [autor] => [autor_email] => [obsah] =>We offer an undergraduate bachelor degree program as well as a master degree program in the Czech language only. For information about study programs in English, please visit the university's website.
Study with us
We offer the research degree program Doctor of Philosophy (PhD) in Organic Chemistry.
Why study for a PhD at our department?
You will become a member of an internationally recognised research team providing high quality research. You will develop the skills and the knowledge needed to pursue your chosen career—in academia, at research organizations, or in public service.
How to apply?
Our prospective student portal provides details about the application process for PhD programmes at UCT Prague.
Our past graduates
Battaglia Caren Bc. (Master Double Degree)
Abdulmanea Khaled Saleh Omar, MSc., PhD (Yemen): Flavonoids in the Apiaceae family (2012)
Irekhjargal Jambal, MSc., PhD (Mongolia): Inhibitors of galactosyltransferases (2012)
Our present students
Uladzimir Bildziukevich, MSc. (Belarus): Steroid-based compounds with potential pharmacologic importance
Jana Šusteková, Ing. (Slovakia): Self-assembly in supramolecular systems based on steroid compounds
Joint-degree doctoral programme graduates
Ing. Ondřej Jurček, PhD (Czechia): Steroid conjugates for applications in pharmacology and biology (2011), with the Faculty of Mathematics and Science, University of Jyväskylä, Finland
Ing. Helena Heissigerová, PhD (Czechia): Glycosyltransferases: Etude comparative, modelisation moleculaire et synthese de nouveaux inhibiteurs (2003), with the Université Joseph Fourier – Grenoble, France
9 We accept students within the framework of the IAESTE exchange programme.
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We offer our partners:
Department of Chemistry of Natural Compounds, Faculty of Food and Biochemical Technology, UCT Prague |
k (+420) 220 444 260 |
Technická 5 |
W (+420) 220 444 422 |
166 28 Praha 6 |
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Head of Department |
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Prof. Dr. RNDr. Oldřich Lapčík |
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k (+420) 220 444 448 |
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b Oldrich.Lapcik@vscht.cz |
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room BS18 |
Secretary of Department |
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Secretary |
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assoc. prof. Ing. Kamil Parkan, Ph.D. |
Irena Dražilová |
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k (+420) 220 444 265 |
k (+420) 220 444 260 |
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b Kamil.Parkan@vscht.cz |
b Irena.Drazilova@vscht.cz |
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website |
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CV |
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building A, room A246 |
building A, room A244 |
The Department of Chemistry of Natural Compounds at the Faculty of Food and Biochemical Technology at UCT Prague was founded in 1991 as the successor to the Laboratory of Monosaccharides. Its mission includes both education and training at the graduate as well as postgraduate level and research and development in several fields crossing the frontier between organic chemistry and biology.
Our department's research aims to understand living systems at the molecular level, providing new molecules with new properties that eventually could become medicines, among other things. It is essential to continue this research at the fundamental level so as to provide tools for designing, synthesizing, and evaluating new functional molecules for targeting applications. Nature is our inspiration.
Key research areas include:
For further details about our research topics, please visit the webpages of individual teams.
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Our main portfolio includes chemistry of: steroid compounds (estradiol, androgens, cardiotonics), mitotic inhibitors (colchicine, taxol), SERCA inhibitors (trilobolide and thapsigargin) and antimalarials (artemisinin), maturation inhibitors HIV-1 (bevirimat).
The group also focuses on the synthesis of fluorophores and fluorescently labeled natural substances. Our favorite fluorophores include BODIPY, but we also work with cyanine and xanthene dyes. This category also includes the conjugation of natural substances with photosensitizers based again on BODIPY, natural chlorins, bacteriochlorins and porphyrins. These products are useful tools for studying the fate of natural substances in living cells using fluorescence microscopy or as potential drugs in photodynamic therapy.
In general, we like to synthesize labeled molecules. These derivatives of natural substances may be important as tools useful in proteomics (biotinylated derivatives, PROTACs). This cathegory includes the preparation of haptens for immunochemical methods.
The link to the publications representing the results of our work is located in the box on the right.
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MASTER THESES
Anna Marešová (consultant Ing. Tomáš Zimmermann, Ph.D.), Synthesis of P2X7 antagonists and their radiolabeling; opponent doc. Ing. Alexander Popkov, Ph.D.; defended 3.6.2021.
Pavel Trousil (conzultant Ing. Tomáš Zimmermann, Ph.D.), Synthesis and characterization of 17α-homodimers of estradiol; opponent RNDr. Jarmila Králová, Ph.D.; defended 3.6.2021.
BACHELOR THESES
Vanda Lupjanová (conzultant Ing. Jan Hajdůch, Ph.D.), Preparation and use of nitrodipyrromethanes for the synthesis of fluorophores with a modifiable amino group; defended 22.6.2021.
Kateřina Váchalová Fluorescent probes for lipoid compounds imaging on live cells; defended 29. 6. 2020.
František Fiala Conjugates of BODIPY with taxol for live-cell imaging and photodynamic therapy in tumor models; defended 29. 6. 2020.
Jan Mazel Maturation inhibitors derived from bevirimat; defended 24. 8. 2020.
Pavel Trousil Synthesis and study of mitotic inhibitors; defended 17. 6. 2019.
CONSULTANT
MASTER THESES
Barbora Baubínová (supervisor prof. Dr. RNDr. Oldřich Lapčík), Fluoroimmunoassay of anabolic steroids; defended 10. 6. 2020.
Jiří Vyšohlíd (supervisor prof. RNDr. Pavel B. Drašar, DSc.), Study of biologically active sesquiterpene lactones of guaianolide type isolated from L. trilobum; defended 6. 6. 2019.
Jiří Bejček (supervisor Ing. Silvie Rimpelová, Ph.D.), Biological activity of novel fluorescently labelled ligands of Na+/K+ ATPase; defended 6. 6. 2018.
Nikita Dovzhenko (supervisor doc. Mgr. Taťjana Šiškanová, CSc.), Modified electrodes for electrochemical detection of psychoactive substances; defended 4. 6. 2018.
David Kodr (supervisor prof. RNDr. Pavel B. Drašar, DSc.), Synthesis of fluorescent labelled betulinic acid derivatives; defended 6. 6. 2018.
Radka Kucherková (supervisor prof. RNDr. Pavel B. Drašar, DSc.), Synthesis and study of analogues of BODIPY dyes; defended 7. 6. 2018.
Tomáš Zimmermann (supervisor prof. RNDr. Pavel B. Drašar, DSc.), Synthesis of new trilobolide derivatives; defended 3. 6. 2015.
Pavla Tomanová (supervisor prof. RNDr. Pavel B. Drašar, DSc.), Synthesis and study of porphyrin-trilobolide conjugates for molecular biology; defended 4. 6. 2014.
BACHELOR THESES
Jiří Vyšohlíd (supervisor prof. RNDr. Pavel B. Drašar, DSc.), Study of sesquiterpene derivatives; defended 27. 6. 2017.
Kryštof Škach (supervisor prof. Ing. Tomáš Ruml, CSc.), Synthesis and study of bombesin analogue with photosenzitizers; defended 23. 6. 2016.
Markéta Šimková (supervisor prof. RNDr. Pavel Drašar, DSc.), Study of components of Laserpitium prutenicum L.; defended 23. 6. 2016.
Radka Kucherková (supervisor prof. RNDr. Pavel B. Drašar, DSc.), Synthesis of fluorescent methoxy derivatives of BODIPY dyes; defended 27. 6. 2016.
David Kodr (supervisor prof. RNDr. Pavel B. Drašar, DSc.), Synthesis of cyproterone photosensitizers conjugates; defended 23. 6. 2016.
Tereza Šimková (supervisor prof. RNDr. Pavel B. Drašar, DSc.), Preparation and study of estradiol derivatives with fluorescent label; defended 25. 6. 2015.
Lucie Poláková (Odstrčilová) (supervisor prof. RNDr. Pavel B. Drašar, DSc.), Preparation of components of immunochemical kits for the detection of bioactive steroids; defended 28. 8. 2015.
Tomáš Zimmermann (supervisor prof. RNDr. Pavel B. Drašar, DSc.), Synthesis and study of tribolide derivatives; defended 26. 6. 2013.
Ludmila Škorpilová (supervisor prof. Ing. Zdeněk Wimmer, DrSc.), Derivatives of cholesterol for visualization of apoptosis; defended 26. 6. 2013.
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Ing. Anna Marešová
Masters's degree
bc. Lukáš Mazur
bc. František Fiala
bc. Jan Mazel
Bachelor's degree
Gabriela Merhoutová