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                                    [seo_desc] => Studies Department of Chemistry of Natural Compounds at the Faculty of Food and Biochemical Technology UCT Prague University of Chemistry and Technology Prague
                                    [autor] => 
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                                    [obsah] => 
We offer an undergraduate bachelor degree program as well as a master degree program in the Czech language only. For information about study programs in English, please visit the university's website.
Study with us 
We offer the research degree program Doctor of Philosophy (PhD) in Organic Chemistry.
Why study for a PhD at our department?
You will become a member of an internationally recognised research team providing high quality research. You will develop the skills and the knowledge needed to pursue your chosen career—in academia, at research organizations, or in public service.
How to apply?
Our prospective student portal provides details about the application process for PhD programmes at UCT Prague. 
Our past graduates
Battaglia Caren Bc. (Master Double Degree)
Abdulmanea Khaled Saleh Omar, MSc., PhD (Yemen): Flavonoids in the Apiaceae family (2012)
Irekhjargal Jambal, MSc., PhD (Mongolia): Inhibitors of galactosyltransferases (2012)
Our present students
Uladzimir Bildziukevich, MSc. (Belarus): Steroid-based compounds with potential pharmacologic importance
Jana Šusteková, Ing. (Slovakia): Self-assembly in supramolecular systems based on steroid compounds
Joint-degree doctoral programme graduates

Ing. Ondřej Jurček, PhD (Czechia): Steroid conjugates for applications in pharmacology and biology (2011), with the Faculty of Mathematics and Science, University of Jyväskylä, Finland
Ing. Helena Heissigerová, PhD (Czechia): Glycosyltransferases: Etude comparative, modelisation moleculaire et synthese de nouveaux inhibiteurs (2003), with the Université Joseph Fourier – Grenoble, France
 
9 We accept students within the framework of the IAESTE exchange programme.
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                                    [autor] =>  
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We are open to cooperation on common projects or through contracts.

We offer our partners:

synthesis of specialty chemicals from natural compounds and their analogs

steroids and other terpeniods
porphyrins
flavonoids
saccharides
glycosides, C-glycosides
non-isotopic labeled compounds



 

prepararion of antibodies, immunogens, tracers and others components of immunoassays
structural analysis
quantitative analysis
consultancy in the development of synhtetic methods
consultancy in the development of analytical methods 
specialty chemicals and immunochemicals from our libraries


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Scientific orientation of the department 

The search for new compounds with novel properties.
Biologically active compounds are our inspiration.


Research topics



Chemistry of steroids and other terpenoids

Prof. RNDr. Pavel Drašar, DSc., EurChem, CChem, CSci, FRSC 




Analytical and bioanalytical methods


Prof. Dr. RNDr. Oldřich Lapčík 




Diagnostic and therapeutic nanosystems


RNDr. Miroslav Ledvina, Ph.D.




Chemistry of triterpenoid supramolecules


Prof. Ing. Zdeněk Wimmer, DrSc.




Structural analysis and molecular modeling


Doc. Dr. Ing. Ivan Raich




Laboratory of forensic analysis of biologically active compounds


doc. Ing. Martin Kuchař, Ph.D.




Chemistry of Saccharides and Glycomimetics


doc. Ing. Kamil Parkan, Ph.D.




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Department of Chemistry of Natural Compounds, Faculty of Food and Biochemical Technology, UCT Prague  



k (+420) 220 444 260




Technická 5      


W (+420) 220 444 422




166 28 Praha 6




 




 





Head of Department

 



Prof. Dr. RNDr. Oldřich Lapčík




k (+420) 220 444 448




b Oldrich.Lapcik@vscht.cz




website




CV




room BS18












Secretary of Department





Secretary 




assoc. prof. Ing. Kamil Parkan, Ph.D.


Irena Dražilová




k (+420) 220 444 265


k (+420) 220 444 260




b Kamil.Parkan@vscht.cz


b Irena.Drazilova@vscht.cz




website


 




 CV



building A, room A246

building A, room A244





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                                    [nazev] => The Department of Chemistry of Natural Compounds
                                    [seo_title] => The Department of Chemistry of Natural Compounds
                                    [seo_desc] => The Department of Chemistry of Natural Compounds UCT Prague University of Chemistry and Technology Prague
                                    [autor] => 
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                                    [obsah] => 
The Department of Chemistry of Natural Compounds at the Faculty of Food and Biochemical Technology at UCT Prague was founded in 1991 as the successor to the Laboratory of Monosaccharides. Its mission includes both education and training at the graduate as well as postgraduate level and research and development in several fields crossing the frontier between organic chemistry and biology.
Our department's research aims to understand living systems at the molecular level, providing new molecules with new properties that eventually could become medicines, among other things. It is essential to continue this research at the fundamental level so as to provide tools for designing, synthesizing, and evaluating new functional molecules for targeting applications. Nature is our inspiration.
Key research areas include:

Chemistry of steroids and other terpenoids
Chemistry of supramolecules with chiral natural compounds
Synthesis of ligands for the cell-cell recognition
The development of nanosensors for the sensing of pathogenic processes
Analytical and bioanalytical methods
Forensic analysis of biologically active compounds
Chemistry of saccharides and glycomimetics
Molecular modeling


The study of the chemical background of natural processes is a huge adventure, which we ourselves enjoy and wish to share with others. —Oldrich Lapcik, Department Chair

For further details about our research topics, please visit the webpages of individual teams.
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DATA

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    [nazev] => Imunochemicals/ Immunochemistry 
    [seo_title] => Imunochemicals
    [seo_desc] => Department of Chemistry of Natural Compounds at the Faculty of Food and Biochemical Technology UCT Prague University of Chemistry and Technology Prague
    [autor] => 
    [autor_email] => 
    [obsah] => 
Imunochemicals /Immunochemistry:
1. Polyclonal rabbit antibodies against a hapten-BSA conjugate
2. Conjujugates of haptens with different carrier proteins (e.g. BSA, OVA)




Analyte


Reference




Polyphenols


 




Biochanin A


Lapčík O. et al., A. J. Immunol. Methods 294: 155-163.  http://www.sciencedirect.com/science/article/pii/S0022175904003047




Coumestrol


Lapčík O. et al.,  Steroids 68: 1147-1155. http://www.sciencedirect.com/science/article/pii/S0039128X03001818




Daidzein


Lapčík O. et al., Steroids 62:315-320. http://www.sciencedirect.com/science/article/pii/S0039128X96002267
Wang G.J. et al, Steroids 65: 339-348.  http://www.sciencedirect.com/science/article/pii/S0039128X00000891




Enterolaktone


Adlercreutz H. et al., Anal. Biochem. 265: 208-215.    http://www.sciencedirect.com/science/article/pii/S000326979892886X




Equol


Brouwers E. et al., J. Steroid Biochem. Molec. Biol.  84: 577-588.  http://www.sciencedirect.com/science/article/pii/S0960076003000712
Sosvorová L. et al., Czech J. Food Sci, 29: 65-72. http://www.agriculturejournals.cz/publicFiles/35016.pdf




Genistein


Lapčík O. et al., J. Steroid Biochem. Molec. Biol. 64: 261-268. http://www.sciencedirect.com/science/article/pii/S0960076097001994
Vítková M. et al., Chem listy 98, 1135-1139
http://www.chemicke-listy.cz/docs/full/2004_12_1135-1139.pdf




O-desmethylangolensin


L´homme R. et al., J. Steroid Biochem. Molec. Biol. 81: 353-361. http://www.sciencedirect.com/science/article/pii/S0960076002000730




Isoprenoids


 




Trilobolide


 Huml L. et al.: Steroids xxx(2016)xxx http://dx.doi.org/10.1016/j.steroids.2016.08.019




Sutherlandioside


 Huml L. et al.: Steroids xxx(2016)xxx http://dx.doi.org/10.1016/j.steroids.2016.08.019




Steroids (natural)


 




17-OH Progesterone


 




Androstendione


 




DHEA


 




7a-OH DHEA


Lapčík O. et al. J. Steroid Biochem. Molec. Biol. 71: 231-237.     http://www.sciencedirect.com/science/article/pii/S0960076099001454




7b-OH DHEA


Lapčík O. et al.,  J. Steroid Biochem. Molec. Biol. 67: 439-445.     http://www.sciencedirect.com/science/article/pii/S0960076098001368




DHT


 




Cortisol

 



Testosterone

 



Steroids (synthetic)


 




Boldenone


Fojtíková L. et al.: Food Anal. Methods. 9 (2016) 3179-3186 http://link.springer.com/article/10.1007/s12161-016-0511-9




Drostenolone


 




Ethinylestradiol


 




Mesterolone


 




Methandienone


 




Nortestosterone


Holubová B. et al. Czech J. Food Sci 31 (5), 514-519. http://www.agriculturejournals.cz/publicFiles/100650.pdf




Oxandrolone


 




Oxymetholone


 




Stanazol


 




Trenbolone


 




Contact address: oldrich.lapcik@vscht.cz
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