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Technická 5
166 28 Prague 6 – Dejvice
IČO: 60461337
VAT: CZ60461373

Data mail: sp4j9ch

Copyright: UCT Prague 2015
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We offer an undergraduate bachelor degree program as well as a master degree program in the Czech language only. For information about study programs in English, please visit the university's website.

Study with us

We offer the research degree program Doctor of Philosophy (PhD) in Organic Chemistry.

Why study for a PhD at our department?

You will become a member of an internationally recognised research team providing high quality research. You will develop the skills and the knowledge needed to pursue your chosen career—in academia, at research organizations, or in public service.

How to apply?

Our prospective student portal provides details about the application process for PhD programmes at UCT Prague. 

Our past graduates

Battaglia Caren Bc. (Master Double Degree)

Abdulmanea Khaled Saleh Omar, MSc., PhD (Yemen): Flavonoids in the Apiaceae family (2012)

Irekhjargal Jambal, MSc., PhD (Mongolia): Inhibitors of galactosyltransferases (2012)

Our present students

Uladzimir Bildziukevich, MSc. (Belarus): Steroid-based compounds with potential pharmacologic importance

Jana Šusteková, Ing. (Slovakia): Self-assembly in supramolecular systems based on steroid compounds

Joint-degree doctoral programme graduates

Ing. Ondřej Jurček, PhD (Czechia): Steroid conjugates for applications in pharmacology and biology (2011), with the Faculty of Mathematics and Science, University of Jyväskylä, Finland

Ing. Helena Heissigerová, PhD (Czechia): Glycosyltransferases: Etude comparative, modelisation moleculaire et synthese de nouveaux inhibiteurs (2003), with the Université Joseph Fourier – Grenoble, France

 

9 We accept students within the framework of the IAESTE exchange programme.

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We are open to cooperation on common projects or through contracts.

We offer our partners:

  • synthesis of specialty chemicals from natural compounds and their analogs
    • steroids and other terpeniods
    • porphyrins
    • flavonoids
    • saccharides
    • glycosides, C-glycosides
    • non-isotopic labeled compounds

 

  • prepararion of antibodies, immunogens, tracers and others components of immunoassays
  • structural analysis
  • quantitative analysis
  • consultancy in the development of synhtetic methods
  • consultancy in the development of analytical methods 
  • specialty chemicals and immunochemicals from our libraries

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Scientific orientation of the department 

  • The search for new compounds with novel properties.
  • Biologically active compounds are our inspiration.

Research topics

Chemistry of steroids and other terpenoids

Prof. RNDr. Pavel Drašar, DSc., EurChem, CChem, CSci, FRSC 

Analytical and bioanalytical methods

Prof. Dr. RNDr. Oldřich Lapčík 

Diagnostic and therapeutic nanosystems

RNDr. Miroslav Ledvina, Ph.D.

Chemistry of triterpenoid supramolecules

Prof. Ing. Zdeněk Wimmer, DrSc.

Structural analysis and molecular modeling

Doc. Dr. Ing. Ivan Raich

Laboratory of forensic analysis of biologically active compounds

doc. Ing. Martin Kuchař, Ph.D.

Chemistry of Saccharides and Glycomimetics

doc. Ing. Kamil Parkan, Ph.D.

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Department of Chemistry of Natural Compounds, Faculty of Food and Biochemical Technology, UCT Prague  

k (+420) 220 444 260

Technická 5      

W (+420) 220 444 422

166 28 Praha 6

 

 

šířka 215px

Head of Department

 

Prof. Dr. RNDr. Oldřich Lapčík

k (+420) 220 444 448

b Oldrich.Lapcik@vscht.cz

website

CV

room BS18

 ◳ Obrázek1 (jpg) → (originál)

Secretary of Department

šířka 215px

Secretary 

assoc. prof. Ing. Kamil Parkan, Ph.D.

Irena Dražilová

k (+420) 220 444 265

k (+420) 220 444 260

b Kamil.Parkan@vscht.cz

b Irena.Drazilova@vscht.cz

website

 

 CV
building A, room A246

building A, room A244

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The Department of Chemistry of Natural Compounds at the Faculty of Food and Biochemical Technology at UCT Prague was founded in 1991 as the successor to the Laboratory of Monosaccharides. Its mission includes both education and training at the graduate as well as postgraduate level and research and development in several fields crossing the frontier between organic chemistry and biology.

Our department's research aims to understand living systems at the molecular level, providing new molecules with new properties that eventually could become medicines, among other things. It is essential to continue this research at the fundamental level so as to provide tools for designing, synthesizing, and evaluating new functional molecules for targeting applications. Nature is our inspiration.

Key research areas include:

  • Chemistry of steroids and other terpenoids
  • Chemistry of supramolecules with chiral natural compounds
  • Synthesis of ligands for the cell-cell recognition
  • The development of nanosensors for the sensing of pathogenic processes
  • Analytical and bioanalytical methods
  • Forensic analysis of biologically active compounds
  • Chemistry of saccharides and glycomimetics
  • Molecular modeling

The study of the chemical background of natural processes is a huge adventure, which we ourselves enjoy and wish to share with others. —Oldrich Lapcik, Department Chair

For further details about our research topics, please visit the webpages of individual teams.

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DATA


stdClass Object
(
    [nazev] => Jitka Moravcová
    [seo_title] => Jitka Moravcová
    [seo_desc] => Jitka Moravcová Department of Chemistry of Natural Compounds at the Faculty of Food and Biochemical Technology UCT Prague University of Chemistry and Technology Prague
    [autor] => 
    [autor_email] => 
    [obsah] => 

Education:

 

1970 – 1975

Institute of Chemical Technology (now: University of Pardubice) Pardubice, master's degree in 1975, organic chemistry

1975 – 1978

Postgraduate study at the Department of Organic Chemistry, ICT Pardubice

1979

PhD in Chemical Sciences at ICT Pardubice

Professional life:

 

1980

Researcher, Laboratory of Monosaccharides, Institute of Chemical Technology Prague (ICT Prague - now: University of Chemistry and Technology, Prague; UCT Prague)

1991 – 1998

Lecturer, Department of Chemistry of Natural Compounds, UCT Prague

1998 - 2005

Assistant professor, Department of Chemistry of Natural Compounds, UCT Prague

2005

Professor, Department of Chemistry of Natural Compounds, UCT Prague

2000 – 2006

Head of the Department of Chemistry of Natural Compounds, UCT Prague

2005 – 2007

Vice-rector for research and development, UCT Prague

2010 – 2011

Vice-dean for education, Faculty of Food and Biochemical Technology, UCT Prague

Teaching:

 

 

Lectures for students of all study levels on the isolation and separation of molecules, on the chemistry of biomolecules and scientific communication.

Supervisor of PhD theses and diploma theses.

Subjects of interest:

 

 

Chemistry and stereochemistry of carbohydrates, synthesis of biological active compounds, molecular recognition, chemistry of natural compounds, reaction mechanisms and analytical methods (HPLC, GCL, CE, IR).

 

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  1. Čopíková J., Wimmer Z., Lapčík O., Cahlíková L., Opletal L., Moravcová J., Drašar P.: Přírodní látky svíravé a trpké chuti, Chem. Listy 108, 1053-1057 (2014).
  2. Čopíková J., Moravcová J., Wimmer Z., Opletal L., Lapčík O., Drašar P.: Náhradní sladidla, Chem. Listy 107, 867-874 (2013).
  3. Jambal I., Kefurt K., Hlaváčková M., Moravcová J: Synthesis of 2-fluoro and 4-fluoro galactopyranosyl phosphonate analogues of UDP-Gal, Res. 360, 31-39 (2012).
  4. Wimmer Z., Opletal L., Čopíková J., Moravcová J., Abdulmanea K.S.O., Lapčík O., Drašar P.: Kovová chuť přírodních látek a jejich derivátů, Listy 106, 926-930 (2012).
  5. I., Kefurt K., Moravcová J.: Inhibitory galaktosyltransferas. Chem. Listy 106, 283-288 (2012).
  6. Kaminský J., Dvořáková H., Štursa J., Moravcová J.: Problems with a conformation assignment of aryl-substituted resorc[4]arenes, Czech. Chem. Commun., 76, 1199-1222 (2011).
  7. Opletal L., Wimmer Z., Čopíková J., Lapčík O., Moravcová J., Cahlíková L., Drašar P.: Slaná chuť přírodních látek a jejich derivátů, Listy 105, 761-765 (2011).
  8. Čopíková J., Moravcová J., Lapčík O., Opletal L., Drašar P.: Přírodní látky chuti chladivé a jejich deriváty, Listy 105, 933-942 (2011).
  9. Lapčík O., Opletal L., Moravcová J., Čopíková J., Drašar P.: Přírodní látky a jejich deriváty chuti pálivé, Listy 105, 452-457 (2011).
  10. Kaplánek R., Polák R., Paleta O., Kefurt K., Moravcová J., Křenová I., Kodíček M.: Perfluoroalkylated derivatives of 6-deoxy-6-ethylamino-D-galactose, 1-deoxy-1-methylamino-D-glucitol, and 1-amino-1-deoxy-D-glucitol: syntheses, hemocompatibility, and effect on perfluorocarbon emulsion, Res. 345 (8), 1008-1014 (2010).
  11. Jurček O., Wimmer Z., Bennetová B., Moravcová J., Drašar P., Šaman D.: Novel Juvenogens (Insect Hormonogenic Agents): Preparation and Biological Tests on Neobellieria bullata, Agric. Food Chem. 57 (22), 10852-10858 (2009).
  12. Šimák O., Staněk J., Moravcová J.: A stereocontrolled synthesis of 3-acetamido-1,3,5-trideoxy-and 1,3,5,6-tetradeoxy-1,5-imino-d-glucitol, Res., 344, 966-971 (2009).
  13. Bubník Z., Čurda L., Kadlec P., Moravcová J., Melzoch K., Šárka E., Šmidrkal J., Půlkrábek J., Chochola J.: Zaměření výzkumu pro využití sacharosy k nepotravinářským účelům v ČR. Listy cukrovarnické a řepařské 125, 28-33- (2009).
  14. Hampl F., Moravcová J., Čopíková J., Opletal L., Lapčík O., Drašar P.: Krása a rozmanitost struktur přírodních antibiotik, Listy 103, 15 – 27 (2009).
  15. Moravcová J.: Vliv fytoestrogenů na symptomy menopausy a rakovinu prsu, Interní Med. 11(10), 517-519 (2008).
  16. Štěpánek P., Dukh M., Šaman D., Moravcová J., Kniežo L., Monti D., Venanzi M., Mancini G., Drašar P.:  Synthesis and solvent driven self-aggregation studies of meso-"C-glycoside"-porphyrin derivatives, & Biomol. Chem., 5(6), 960-970 (2007).
  17. Klein P., Moravcová J., Kleinová T., Volek Z., Skřivanová V.: Assessment of intestinal permeability in preruminant calves by lactulose/mannitol test, Anim. Feed Sci., 16, 43-52 (2007).
  18. Moravcová J., Opletal L., Lapčík O., Čopíková J., Uher M., Drašar P.: Látky ovlivňující vnímání organoleptických vlastností, Listy 101, 1002 – 1010 (2007).
  19. Lapčík O., Čopíková J., Uher M., Moravcová J., Drašar P.: Necukerné přírodní látky chuti sladké,Listy 101, 44−54 (2007).
  20. Opletal L., Čopíková J., Uher M., Lapčík O., Moravcová J., Drašar P.: Přírodní látky hořké chuti, Listy 101, 895−906 (2007).
  21. Heissigerová H., Kočalka P., Hlaváčková M., Imberty A., Breton C., Chazalet V., Moravcová J.: Synthesis of d-galactopyranosylphosphonic and (d-galactopyranosylmethyl)phosphonic acids as intermediates of inhibitors of galactosyltransferases, Czech. Chem. Commun., 71, 1659-1672 (2006).
  22. Šaman D., Kratina P., Moravcová J., Wimmerová M., Wimmer Z.: Synthesis and structure assignment of 2-(4-methoxybenzyl)cyclohexyl-b-d-glucopyranoside enantiomers, Czech. Chem. Commun., 71, 1470-1483 (2006).
  23. Dvořáková H., Štursa J., Čajan M., Moravcová J.: Synthesis and Conformational Properties of Partially Alkylated Methylene-Bridged Resorc[4]arenes – Study of the “Flip-Flop” Inversion, J. Org. Chem., 2006, 4519 – 4527.
  24. Lojková L., Klejdus B., Moravcová J., Kubáň V.: Supercritical fluid extraction (SFE) of 4(5)-methylimidazole (4-MeI) and 2-acetyl-4(5)-(1,2,3,4)-tetrahydroxybutyl-imidazole (THI) from ground-coffee with high-performance liquid chromatographic-electrospray mass spectrometric quantification (HPLC/ESI-MS), Food Additives Contam. 23 (10), 963-973 (2006).
  25. Klejdus B., Moravcová J., Lojková L., Vacek J., Kubáň V.: Solid-phase extraction of 4(5)-methylimidazole (4Mel) and 2-acetyl-4(5)-(1,2,3,4-tetrahydroxybutyl)-imidazole(THI) from foods and beverages with subsequent liquid chromatographic-electrospray mass spectrometric quantification, Sep. Sci. 29 (3), 378-384 (2006).
  26. Čopíková J., Lapčík O., Uher M., Moravcová J., Drašar P.: Cukerná nesacharosová sladidla a příbuzné látky, Listy 100, 778 – 783 (2006).
  27. Popelová A., Kefurt K., Hlaváčková M., Moravcová J.: A concise synthesis of 4-nitrophenyl 2-azido-2-deoxy and 2-acetamido-2-deoxy-d-mannopyranosides, Res., 340, 161-166 (2005).
  28. Klejdus B., Lojková L., Lapčík O., Koblovská R., Moravcová J., Kubáň V.: Supercritical fluid extraction of isoflavones from biological samples with ultra-fast high-performance liquid chromatography/mass spectrometry, Sep. Sci., 28, 1334-1346 (2005).
  29. Gros L., Zeller W., Moravcová J.: Evropský prostor pro vzdělávání v chemii, Listy 99(1), 63 (2005).
  30. Čopíková J., Uher M., Lapčík O., Moravcová J., Drašar P.: Přírodní barevné látky, Listy 99 (11), 802-16 (2005).
  31. Lapčík O., Klejdus B., Davidová M., Kokoška L., Kubáň V., Moravcová J.: Isoflavonoids in the Rutaceae family: 1. Fortunella obovata, Murraya paniculata and four Citrus Phytochem. Anal., 15, 293-299 (2004).
  32. Moravcová J., Kleinová T., Loučka R., Tyrolová I., Kvasnička F., Dušek M., Čeřovský M., Matucha P.: The Coumestrol Content in Alfalfa Following Ensilage, Feed Sci. Technol. 115, 159-167 (2004).
  33. Dušek M., Kvasnička F., Moravcová J.: Stanovení organických kyselin v silážích kapilární isotachoforesou a kapilární elektroforesou, Listy 98, 418-422 (2004).
  34. Stursa J., Dvorakova H., Smidrkal J., Petrickova H., Moravcova J.: A novel synthesis of parent resorc[4]arene and its partial alkyl ethers, Tetrahedron Lett., 45, 2043-2046 (2004).
  35. Církva V., Polák R., Paleta O., Kefurt K., Moravcová J., Kodíček M., Forman S.: Novel perfluoroalkytated derivatives of d-galactopyranose and xylitol for biomedical uses. Hemocompatibility and effect on perfluorocarbon emulsions. Res. 339, 2177-2185 (2004).
  36. Oščendová M., Moravcová J.: Kinetics of methylation of methyl 5-deoxy-a/b-d-xylofuranosides.Czech. Chem. Commun., 69, 1877-1888 (2004).
  37. Drašar P., Moravcová J.: Recent advances in analysis of Chinese medical plants and traditional medicines, Chromatogr. B, 812, 3-21(2004).
  38. Klejdus B., Moravcová J., Kubáň V.: Reversed-phase high-performance liquid chromatographic/mass spectrometric method for separation of 4-methylimidazole and 2-acetyl-4-(1,2,3,4-tetrahydroxybutyl)imidazole at pg levels, Chim. Acta, 477, 49 – 58 (2003).
  39. Moravcová J., Kleinová T., Loučka R., Tyrolová I., Kvasnička F., Dušek M., Čeřovský M.: Effect of Additives on Coumestrol Content in Laboratory Alfalfa Silages, J. Anim. Sci., 48, 425-431 (2003).
  40. Heissigerová H., Breton C., Moravcová J., Imberty A.: Molecular modeling of glycosyltransferases involved in the biosynthesis of blood group A, blood group B, Forssman, and iGb3 antigens and their interaction with substrates, Glycobiology 13(5), 377 – 386 (2003).
  41. Lapčík O., Štursa J., Kleinová T., Vítková M., Dvořáková H., Moravcová J., Klejdus B.: Synthesis of hapten and conjugates of coumestrol and development of immunoassay, Steroids 68, 1147-1155 (2003).
  42. Moravcová J., Heissigerová H., Kočalka P., Imberty A., Sýkora D., Fris M.: A novel seven-membered carbohydrate phostone, Tetrahedron Lett. 44, 8797 – 8800 (2003).
  43. Moravcová J., Kleinová T., Loučka R.: The Determination of Coumestrol in Alfalfa (Medicago sativa), Plant Prod., 48, 224-229 (2002).
  44. Moravcová J., Kleinová T.: Fytoestrogeny ve výživě – přinášejí užitek nebo riziko? Listy 96 (5), 282-289 (2002).
  45. Breton C., Heissigerová H., Jeanneau C., Moravcová J., Imberty A.: Comparative aspects of glycosyltransferases, Soc. Symp., 69, 23-32 (2002).
  46. Kefurt K., Moravcová J., Bambasová Š., Buchalová K., Vymětalíková B., Kefurtová Z., Staněk J., Paleta O.: Alkylation of Partially Protected Xylofuranoses and Tetritols with (2,2,3,3,4,4,5,5,6,6,7,7,7-Tridecafluoroheptyl)oxirane and the Stability of Protecting Acetal Groups Towards Lewis Acid-Type Catalyst, Czech. Chem. Commun., 66, 1665-1681 (2001).
  47. Vänttinen K., Moravcová J.: Transdermal absorption of phytoestrogens, Pharmazie 56, 711-717 (2001).
  48. Moravcová J.: Sacharosa jako chemická surovina, Listy 95 (4), 202-211 (2001). – článek získal cenu K. Preise za nejlepší článek uveřejněný v Chemických listech v roce 2001.
  49. Moravcová J., Kefurt K., Hladůvková R., Staněk J.: Pig-liver Esterase Catalyzed Hydrolysis of Methyl Tri-O-acetyl-b-D-arabinopyranoside, Methyl Tri-O-acetyl-b-D-ribopyranoside and Methyl Tri-O-acetyl-b-D-ribofuranoside, Czech. Chem. Commun., 65 (10), 1619 – 1629 (2000).
  50. Moravcová J., Špilová L., Čapková J., Chery F., Rollin P.: Mitsunobu Transformations of 1,2-O-Isopropylidene-a-D-pentofuranoses Mediated by Zinc Salts, Czech. Chem. Commun., 65, 1745-1753 (2000).
  51. Loučka R., Machačová E., Moravcová J., Čeřovský M., Voldřich M.: Vliv komplexu celulázy, hemicelulázy a glukózaoxidázy v probioticko-enzymatickém aditivu na fermentaci vojtěšky, J. Anim. Sci., 44, 87 – 92 (1999).
  52. Gueyrard D., Lorin C., Moravcová J., Rollin P.: A New Intramolecular Migration in Thiosugar Chemistry: S®O Transfer of a Benzthiazol-2-yl Group in Saccharidic Sulfones, Carbohydr. Chem., 18, 317 - 331 (1999).
  53. Moravcová J., Hamerník I., Funková G., Kefurt K., PLE Catalyzed Hydrolysis of Methyl 2,3-O-di-acetyl-5-deoxy-a- and b-D-arabinofuranosides, Carbohydr. Chem., 17, 1191-1202 (1998).
  54. Havlíčková H., Moravcová J.: Sugar Metabolism of Winter Wheat Cultivars Stressed with Ceral Aphids, Prod., 44, 81 - 87 (1998).
  55. Moravcová J., Čapková J., Staněk J. jr., Raich I.: Methyl 5-Deoxy-a- and b-D-xylofuranosides,Carbohydr. Chem., 16, 1061 - 1073 (1997).
  56. Moravcová J., Vanclová Z., Čapková J., Kefurt K., Staněk J. jr.: Enzymic Hydrolysis of Methyl 2,3-Di-O-acetyl-5-deoxy-a- and b-D-xylofuranosides and Active-site Model of Pig Liver Esterase,Carbohydr. Chem., 16, 1011 - 1028 (1997).
  57. Moravcová J., Rollin P., Lorin Ch., Gardon V., Čapková J., Mazáč J.: Regioselective Mitsunobu Thiofunctionalization of Pentofuranoses, Carbohydr. Chem., 16, 113 - 127 (1997).
  58. Moravcová J., Staněk J. jr., Čapková J., Loučka R.: Stanovení sacharosy, glukosy a fruktosy v rostlinách kapalinovou chromatografií na silně kyselém iontoměniči, Výroba 43, 287 - 292 (1997).
  59. Moravcová J., Čeřovský M., Loučka R., Voldřich M., Opatová H., Machačová E.: Vliv glukosooxidasy na obsah sacharosy, glukosy a fruktosy při silážování trávy jílkového typu a vojtěšky, Živočiš. Výroba 42, 223 - 228 (1997).
  60. Čeřovský M., Loučka R., Machačova E., Voldřich M., Opatová H., Moravcová J.: Vliv probioticko-enzymových preparátů na silážovatelnost trávy (Lolium multiflorum) a vojtěšky (Medicago sativa), Živočiš. Výroba 42, 323 - 329 (1997).
  61. Moravcová J., Čapková J., Staněk J. jr.: One-pot Synthesis of 1,2-O-isopropylidene-a-D-xylofuranose, Res., 263, 61 – 66 (1994).
  62. Juříček M., Grúz P., Velemínský J., Staněk J. jr., Kefurt K., Moravcová J., Jarý J.: Mutagenic Activity of 6-Azidodeoxyhexoses and Azidoalcohols in Salmonella Typhimurium and its Inhibition by a Structure-similar Carbon Source in the Medium, Res., 251, 13 – 20 (1991).
  63. Moravcová J.: Metody stanovení 4-methylimidazolu v kuléru, Vědy, 9, 307 (1991).
  64. Gonzales G., Pérez M., Santana I., Marcet M., Staněk J. jr., Moravcová J., Jarý J.: Mutagenic Activity of 3-Azido-1,2-propanediol and Sodium Azide Applied to Sugar Cane Callus Cells, Biologia Plantarum, 32, 388 – 390 (1990).
  65. Juříček M., Grúz P., Velemínský J., Staněk J. jr., Moravcová J., Jarý J.: High Mutagenic Activity of 3-Azido-1,2-propandiol (azidoglycerol, AG) in strain D7 of Saccharomyces Cerevisiae, Res., 178, 43 – 47 (1987).
  66. Juříček M., Velemínský J., Jefremová G. J., Kočišová J., Gichner T., Staněk J. jr., Moravcová J., Jarý J.: Comparative Mutagenicity of 3-Azido-1,2-propanediol and Sodium Azide in Various Pro- and Eukaryote Systems, Res., 179, 175–182 (1987).
  67. Čapek K., Vodrážková-Medonosová M., Moravcová J., Sedmera P.: Partially Acetylated Sucrose. Structures of Hepta-O-acetylsucroses Formed by Deacetylation of Octa-O-acetylsucrose, Czechoslov. Chem. Commun., 51, 1476 – 1486 (1986).
  68. Staněk J. jr., Moravcová J., Jarý J.: Crystalline Methyl-b-L-rhamnofuranoside in Fischer Glycosidation of L-Rhamnose, Carbohydr. Chem., 4, 79 – 90 (1985).
  69. Moravcová J., Večeřa M.: Kinetics and Mechanism of Hydrolysis of Substituted Phenyl N-(4-methylfenyl)sulfonylcarbamates. Solvolysis of 3-Nitrofenyl N-(4-methylfenyl)sulfonylcarbamate in Mixtures Water-1,4-Dioxane and Water-tert.butylalcohol and its Decomposition to Neutral Molecules in Non-aqueous Media, Czechoslov. Chem. Commun., 44, 2639- 2651 (1979).
  70. Moravcová J., Večeřa M.: Kinetics and Mechanism of Hydrolysis of Aryl N-trichloroacetylcarbamates, Czechoslov. Chem. Commun., 42, 3048 – 3056 (1977).

 

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