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Technická 5
166 28 Prague 6 – Dejvice
IČO: 60461337
VAT: CZ60461373
Data mail: sp4j9ch
Copyright: UCT Prague 2015
Information provided by the Department of International Relations and the Department of R&D. Technical support by the Computing Centre.
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[obsah] => We offer an undergraduate bachelor degree program as well as a master degree program in the Czech language only. For information about study programs in English, please visit the university's website.
Study with us
We offer the research degree program Doctor of Philosophy (PhD) in Organic Chemistry.
Why study for a PhD at our department?
You will become a member of an internationally recognised research team providing high quality research. You will develop the skills and the knowledge needed to pursue your chosen career—in academia, at research organizations, or in public service.
How to apply?
Our prospective student portal provides details about the application process for PhD programmes at UCT Prague.
Our past graduates
Battaglia Caren Bc. (Master Double Degree)
Abdulmanea Khaled Saleh Omar, MSc., PhD (Yemen): Flavonoids in the Apiaceae family (2012)
Irekhjargal Jambal, MSc., PhD (Mongolia): Inhibitors of galactosyltransferases (2012)
Our present students
Uladzimir Bildziukevich, MSc. (Belarus): Steroid-based compounds with potential pharmacologic importance
Jana Šusteková, Ing. (Slovakia): Self-assembly in supramolecular systems based on steroid compounds
Joint-degree doctoral programme graduates
Ing. Ondřej Jurček, PhD (Czechia): Steroid conjugates for applications in pharmacology and biology (2011), with the Faculty of Mathematics and Science, University of Jyväskylä, Finland
Ing. Helena Heissigerová, PhD (Czechia): Glycosyltransferases: Etude comparative, modelisation moleculaire et synthese de nouveaux inhibiteurs (2003), with the Université Joseph Fourier – Grenoble, France
9 We accept students within the framework of the IAESTE exchange programme.
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[autor] =>
[autor_email] =>
[obsah] => We are open to cooperation on common projects or through contracts.
We offer our partners:
- synthesis of specialty chemicals from natural compounds and their analogs
- steroids and other terpeniods
- porphyrins
- flavonoids
- saccharides
- glycosides, C-glycosides
- non-isotopic labeled compounds
- prepararion of antibodies, immunogens, tracers and others components of immunoassays
- structural analysis
- quantitative analysis
- consultancy in the development of synhtetic methods
- consultancy in the development of analytical methods
- specialty chemicals and immunochemicals from our libraries
Scientific orientation of the department
- The search for new compounds with novel properties.
- Biologically active compounds are our inspiration.
Research topics
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Department of Chemistry of Natural Compounds, Faculty of Food and Biochemical Technology, UCT Prague |
k (+420) 220 444 260 |
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Technická 5 |
W (+420) 220 444 422 |
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166 28 Praha 6 |
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Head of Department |
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Prof. Dr. RNDr. Oldřich Lapčík |
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k (+420) 220 444 448 |
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b Oldrich.Lapcik@vscht.cz |
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room BS18 |
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Secretary of Department |
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Secretary |
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assoc. prof. Ing. Kamil Parkan, Ph.D. |
Irena Dražilová |
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k (+420) 220 444 265 |
k (+420) 220 444 260 |
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b Kamil.Parkan@vscht.cz |
b Irena.Drazilova@vscht.cz |
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website |
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CV |
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| building A, room A246 |
building A, room A244 |
The Department of Chemistry of Natural Compounds at the Faculty of Food and Biochemical Technology at UCT Prague was founded in 1991 as the successor to the Laboratory of Monosaccharides. Its mission includes both education and training at the graduate as well as postgraduate level and research and development in several fields crossing the frontier between organic chemistry and biology.
Our department's research aims to understand living systems at the molecular level, providing new molecules with new properties that eventually could become medicines, among other things. It is essential to continue this research at the fundamental level so as to provide tools for designing, synthesizing, and evaluating new functional molecules for targeting applications. Nature is our inspiration.
Key research areas include:
- Chemistry of steroids and other terpenoids
- Chemistry of supramolecules with chiral natural compounds
- Synthesis of ligands for the cell-cell recognition
- The development of nanosensors for the sensing of pathogenic processes
- Analytical and bioanalytical methods
- Forensic analysis of biologically active compounds
- Chemistry of saccharides and glycomimetics
- Molecular modeling
The study of the chemical background of natural processes is a huge adventure, which we ourselves enjoy and wish to share with others. —Oldrich Lapcik, Department Chair
For further details about our research topics, please visit the webpages of individual teams.
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(
[nazev] => Ivan Raich
[seo_title] => Ivan Raich
[seo_desc] => Ivan Raich Department of Chemistry of Natural Compounds at the Faculty of Food and Biochemical Technology UCT Prague University of Chemistry and Technology Prague
[autor] =>
[autor_email] =>
[obsah] =>
Ivan Raich, PhD, assoc. prof. |
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Education: |
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1982-1986 |
M.S. studies: University of Chemistry and Technology, Prague, Faculty of Food and Biochemical Technology |
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M.S. thesis: Partial acetylation and deacetylation of methyl α- and β‑D‑threofuranoside and methyl α- and β‑D‑erythrofuranoside |
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Supervisor: prof. Jiří Jarý |
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1986-1994 |
PhD studies: UCT Prague, FFBT |
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PhD: Methyl erythrosides with aziridine, oxirane and thiirane ring |
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Supervisor: prof. Jiří Jarý, assoc. prof. Jan Staněk |
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2012 |
Associate professor in Organic chemistry, UCT Prague, FFBT |
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Practice: |
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1986-1988 |
PhD studies, UCT Prague, FFBT, Laboratory of monosaccharides |
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1988-1989 |
military service |
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1989-1993 |
PhD studies, UCT Prague, FFBT, Laboratory of monosaccharides, Department of Chemistry of Natural Compounds |
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1993-present |
UCT Prague, Department of Chemistry of Natural Compounds |
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1993-1995 |
senior researcher |
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1995-2012 |
assistant professor |
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2012-present |
associate professor |
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Teaching: |
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Computer technology |
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Applied computer technology |
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Chemical informatics |
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Bioinformatics |
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Analytical and forensic databases |
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Molecular modeling |
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Laboratory practice in isolation and separation methods |
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Scientific interests: |
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Stereochemistry and conformational analysis of mono- and disaccharides and other natural compounds |
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Molecular modeling and dynamics of bioorganic molecules |
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QM calculations of spectra and chiroptical properties |
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Solvation of biomolecules |
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Theoretical and experimental study of reaction mechanisms |
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Makrlík E., Böhm S., Vaňura P., Raich I.: Extraction and DFT study on interaction of the cesium cation with enniatin B, J. Mol. Struct. 2014, 1076, 564-567. Online |
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Makrlík E., Böhm S., Vaňura P., Raich I.: Extraction and DFT study on the complexation of the strontium cation with enniatin B, Chem. Phys. 2014, 439(0), 95-99. Online |
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Brychtová K., Dvořáková L., Opatřilová R., Raich I., Káčerová S., Plaček L., Kalinowski D. S., Richardson D. R., Jampílek J.: Investigation of substituted 6-aminohexanoates as skin penetration enhancers, Bioorg. Med. Chem. 2012, 20(1), 86-95. Online |
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Mandelová Z., Opatřilová R., Raich I., Havlíček J., Káčerová S., Pekárek T., Tkadlecová M., Stašková P., Dohnal J., Csollei J., Jampílek J.: Synthesis, physico-chemical properties and DFT calculations of new 2-(4-arylpiperazine-1-yl)-1-(3-ethylbenzofuran-2-yl)ethanols as potential antihypertensive agents, Current Organic Chemistry 2011, 15(7), 1081-1096. Online |
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Kaminský J., Raich I., Tomčáková K., Bouř P.: Conformational behavior of simple furanosides studied by optical rotation, J. Comput. Chem. 2010, 31(11), 2213-2224. Online |
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Brychtová K., Opatřilová R., Raich I., Kalinowski D. S., Dvořáková H., Plaček L., Csollei J., Richardson D. R., Jampílek J.: Investigating the activity of 2-substituted alkyl-6-(2,5-dioxopyrrolidin-1-yl)hexanoates as skin penetration enhancers, Bioorg. Med. Chem. 2010, 18(24), 8556-8565. Online |
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Brychtová K., Jampílek J., Opatřilová R., Raich I., Farsa O., Csollei J.: Synthesis, physico-chemical properties and penetration activity of alkyl-6-(2,5-dioxopyrrolidin-1-yl)-2-(2-oxopyrrolidin-1-yl)hexanoates as potential transdermal penetration enhancers, Bioorg. Med. Chem. 2010, 18(1), 73-79. Online |
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Opatřilová R., Jampílek J., Raich I., Káčerová S., Havlíček J., Pekárek T., Dohnal J., Csollei J.: Synthesis, characterization and physicochemical properties of new 2-(4-arylpiperazin-1-yl)-1-(3-methylbenzofuran-2-yl)ethanols as potential antihypertensive agents, Current Organic Chemistry 2009, 13(10), 965-975. Online |
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Brychtová K., Slabá B., Plaček L., Jampílek J., Raich I., Csollei J.: Coupling reactions of α-bromocarboxylate with non-aromatic N-heterocycles, Molecules 2009, 14(8), 3019-3029. Online |
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Kaminský J., Raich I.: Stereochemical preference of nucleophilic cleavage in methyl erythrofuranosides explained by density functional theory computations, J. Mol. Struct.: THEOCHEM 2008, 860(1-3), 32-39. Online |
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Jampílek J., Řečková Z., Imramovský A., Raich I., Vinšová J., Dohnal J.: Study of stability of new mutual prodrugs with antimycobacterial activity, Current Organic Chemistry 2008, 12(8), 667-674. Online |
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Vích O., Kniežo L., Dvořáková H., Raich I., Valenta Š.: Conformational preferences of ethyl 2,3-dideoxy-3-[(α-D-glucopyranosyl)methyl]-β-L- and -D-arabino-hexopyranosides, Collect. Czech. Chem. Commun. 2005, 70(12), 2086-2100. Online |
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Jampílek J., Doležal M., Kuneš J., Šatínský D., Raich I.: Novel regioselective preparation of 5-chloropyrazine-2-carbonitrile from pyrazine-2-carboxamide and coupling study of substituted phenylsulfanylpyrazine-2-carboxylic acid derivatives, Current Organic Chemistry 2005, 9(1), 49-60. Online |
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Jampílek J., Doležal M., Kuneš J., Raich I., Liška F.: 4-substituted aryl bromides coupling with 4-methoxybenzene-1-thiol by means of copper catalysts, Chemical Papers 2005, 59(3), 182-186. |
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Synytsya A., Urbanová M., Setnička V., Tkadlecová M., Havlíček J., Raich I., Matějka P., Synytsya A., Čopíková J., Volka K.: The complexation of metal cations by D-galacturonic acid: a spectroscopic study, Carbohydr. Res. 2004, 339(14), 2391-2405. Online |
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Jampílek J., Doležal M., Kuneš J., Víchová P., Raich I., Jun D., O'Connor R., Clynes M.: Preparation of 2-(4-{[4-(quinolin-2-ylmethoxy)phenyl]sulfanyl}phenyl)propionic acid (VUFB 20615) and 2-methyl-2-(4-{[4-(quinolin-2-ylmethoxy)phenyl]sulfanyl}phenyl)propionic acid (VUFB 20623) as potential antileukotrienic agents, Current Organic Chemistry 2004, 8(13), 1235-1243. Online |
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Bouř P., Raich I., Kaminský J., Hrabal R., Čejka J., Sychrovský V.: Restricted Conformational Flexibility of Furanose Derivatives: Ab Initio Interpretation of Their Nuclear Spin-Spin Coupling Constants, J. Phys. Chem. A 2004, 108(30), 6365-6372. Online |
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Raich I.: The use of molecular modeling in industry, CHEMagazin 1997, 7(5), 28-29. |
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Moravcová J., Čapková J., Staněk J., Raich I.: Methyl 5-deoxy-α and β-D-xylofuranosides, J. Carbohydr. Chem. 1997, 16(7), 1061-1073. Online |
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Jarý J., Raich I.: Synthesis of methyl 2,3-anhydro-α- and -β-L-erythrofuranoside, Carbohydr. Res. 1993, 242, 291-295. Online |
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Marek M., Raich I., Kefurt K., Jarý J., Rouwenhorst I. M.: Enzymic deacetylation of methyl 2,3-di-O-acetyl-α- and β-D-threofuranoside, Biocatalysis 1992, 6(2), 135-143. Online |
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Jarý J., Marek M., Raich I.: Partial methylation of methyl α-D- and β-D-threofuranoside, Collect. Czech. Chem. Commun. 1990, 55(7), 1777-1782. Online |
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